Peer-Reviewed Publications

Peer-Reviewed Publications | Steadman Philippon Research Institute

Steadman Philippon Research Institute (SPRI) is one of the most published organizations in orthopaedic and sports medicine research. PubMed, a free search engine maintained by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), is a foundational global index of biomedical and life science literature. Below, SPRI's peer-reviewed publications are listed through PubMed's index.

SPRI is the #1 publisher in joint preservation and orthopaedic sports medicine worldwide, and has published more papers in the top 1% of cited publications than any other organization.

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14 publications

Short-Term Cryopreservation Preserved the Function of MSCs from Bone Marrow Aspirate Concentrate

Singer J, Nishimura H, Xiao Z, Gao X, Knezic N, Chubb L, Layne JE, Guo P, Lu A, Huard J

SPRI Jonny Layne, Jacob Singer, Haruki Nishimura, Ping Guo, Xueqin Gao, Aiping Lu, Johnny Huard

Cells · 2025 Oct 9 · 14(19)

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Muscle-specific ERRγ activation mitigates muscle atrophy after ACL injury

Lu A, Sikes KJ, Guo P, Huard M, Green S, Santangelo K, Singer J, Groesbeck A, Tashman S, Narkar VA, Huard J

SPRI Shelby Green, Jacob Singer, Scott Tashman, Matthieu Huard, Ping Guo, Aiping Lu, Scott Tashman, Johnny Huard

FASEB J · 2025 Feb 28 · 39(4):e70409

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TIPE2 gene transfer ameliorates aging-associated osteoarthritis in a progeria mouse model by reducing inflammation and cellular senescence

Guo P, Gao X, Nelson AL, Huard M, Lu A, Hambright WS, Huard J

SPRI Matthieu Huard, Ping Guo, Xueqin Gao, Aiping Lu, Anna-Laura Nelson, Johnny Huard

Mol Ther · 2024 Sep 4 · 32(9):3101-3113

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Clinical validation of C(12)FDG as a marker associated with senescence and osteoarthritic phenotypes

Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Robbins PD, Niedernhofer LJ, Kirkland JL, Bahney CS, Philippon M, Huard J

SPRI Lucas Minas, John Mitchell, Ping Guo, Xueqin Gao, Aiping Lu, Marc J. Philippon, Johnny Huard

Aging Cell · 2024 May · 23(5):e14113

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The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24 (-/-) Progeria Mouse Model

Hambright WS, Mu X, Gao X, Guo P, Kawakami Y, Mitchell J, Mullen M, Nelson AL, Bahney C, Nishimura H, Hellwinkel J, Eck A, Huard J

SPRI Haruki Nishimura, John Mitchell, Ping Guo, Xueqin Gao, Anna-Laura Nelson, Johnny Huard

J Osteoporos · 2023 · 2023:5572754

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Specific reprogramming of alpha cells to insulin-producing cells by short glucagon promoter-driven Pdx1 and MafA

Guo P, Zhang T, Lu A, Shiota C, Huard M, Whitney KE, Huard J

SPRI Matthieu Huard, Ping Guo, Aiping Lu, Johnny Huard

Mol Ther Methods Clin Dev · 2023 Mar 9 · 28:355-365

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In vitro analysis of genome-engineered muscle-derived stem cells for autoregulated anti-inflammatory and antifibrotic activity

Pferdehirt L, Guo P, Lu A, Huard M, Guilak F, Huard J

SPRI Matthieu Huard, Ping Guo, Aiping Lu, Johnny Huard

J Orthop Res · 2022 Dec · 40(12):2937-2946

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The role of the aging microenvironment on the fate of PDGFRβ lineage cells in skeletal muscle repair

Lu A, Tseng C, Guo P, Gao Z, Whitney KE, Kolonin MG, Huard J

SPRI Ping Guo, Aiping Lu, Johnny Huard

Stem Cell Res Ther · 2022 Aug 5 · 13(1):405

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VEGF-attenuated platelet-rich plasma improves therapeutic effect on cartilage repair

Lee JS, Guo P, Klett K, Hall M, Sinha K, Ravuri S, Huard J, Murphy WL

SPRI Ping Guo, Johnny Huard

Biomater Sci · 2022 May 4 · 10(9):2172-2181

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Enhancement of myogenic potential of muscle progenitor cells and muscle healing during pregnancy

Lu A, Guo P, Pan H, Tseng C, Sinha KM, Yang F, Scibetta A, Cui Y, Huard M, Zhong L, Ravuri S, Huard J

SPRI Matthieu Huard, Ping Guo, Aiping Lu, Johnny Huard

FASEB J · 2021 Mar · 35(3):e21378

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Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy

Lu A, Guo P, Wang L, Tseng C, Huard M, Allen C, McCarrick-Walmsley R, Whitney KE, Huard J

SPRI Matthieu Huard, Ping Guo, Aiping Lu, Johnny Huard

Sci Rep · 2020 Apr 27 · 10(1):7075

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Hypoxia-inducible factor 1α (HIF-1α) is a major determinant in the enhanced function of muscle-derived progenitors from MRL/MpJ mice

Sinha KM, Tseng C, Guo P, Lu A, Pan H, Gao X, Andrews R, Eltzschig H, Huard J

SPRI Ping Guo, Xueqin Gao, Aiping Lu, Johnny Huard

FASEB J · 2019 Jul · 33(7):8321-8334

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TIPE2 gene transfer with adeno-associated virus 9 ameliorates dystrophic pathology in mdx mice

Gao S, Lu A, Amra S, Guo P, Huard J

SPRI Ping Guo, Aiping Lu, Johnny Huard

Hum Mol Genet · 2019 May 15 · 28(10):1608-1619

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Markers of Accelerated Skeletal Muscle Regenerative Response in Murphy Roths Large Mice: Characteristics of Muscle Progenitor Cells and Circulating Factors

Tseng C, Sinha K, Pan H, Cui Y, Guo P, Lin CY, Yang F, Deng Z, Eltzschig HK, Lu A, Huard J

SPRI Ping Guo, Aiping Lu, Johnny Huard

Stem Cells · 2019 Mar · 37(3):357-367

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